Kenneth Kin Lam Wong*, Negin Imani Farahani*, George Allen, Abhimanyu Minhas and Lisa M Julian. Protocol for the generation of micropatterned neuroepithelial tissues using hPSCs, bioprinting and matrix scaffolds. STAR-PROTOCOLS-D-25-00497 (2025). In press.

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Negin Imani Farahani*, Kenneth Kin Lam Wong*, George Allen, Abhimanyu Minhas, Lisa Lin, Shama Nazir, and Lisa M Julian. A bioprinting approach for high-throughput production of micropatterned neuroepithelial tissues and modeling TSC2-deficient brain malformations. (2025). Cell Reports Methods (2025). 17:101177. Link

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Samantha Rothwell, Irving Ng, Sophia Shalchy-Tabrizi, Pola Kalinowski, Omnia M Taha, Italia Paris, Angelica Baniqued, Lisa Lin, Michelle Mezei, Anna Lehman, Lisa M Julian, Damon Poburko. Loss-of-function mitochondrial DNA polymerase gamma variants cause vascular smooth muscle cells to secrete diffusible mitogenic factor. Front Physiol (2025). 15:1488248. Link

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Orr A, Kalantarnia F, Nazir S, Bolandi B, Alderson D, O'Grady K, Hoorfar M, Julian LM, Willerth SM. Recent advances in 3D bioprinted neural models: A systematic review on the applications to drug discovery. Adv Drug Deliv Rev. (2025). 218:115524. Link

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Imani Farahani N, Lin L, Nazir S, Naderi A, Rokos L, McIntosh AR, Julian LM^. Advances in physiological and clinical relevance of hiPSC-derived brain models for precision medicine pipelines. Front Cellular Neurosci (2025). 18:1478572. Link

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Daughters RS, Julian L, Knock E, Willerth SM. Editorial: Next generation in vitro models of the human blood - brain/cerebrospinal fluid barrier. Front Mol Neurosci (2024) 17:1371733. Pubmed

 

Nazir S, Feresten AH, Lin L, Hutter H, Julian LM. Extracellular Matrix of the Nervous System. Handbook of Neural Engineering: A Modern Approach. Elsevier (2023). Link

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Dawoody Nejad L, Julian LM. Stem cell-derived organoid models for SARS-CoV-2 and its molecular interaction with host cells. Mol Biol Rep. (2023). 50(12): 10627-10635 Pubmed

 

Pietrobon A, Yockell-Lelièvre J, Melong N, Smith LJ, Delaney SP, Azzam N, Xue C, Merwin N, Lian E, Camacho-Magallanes A, Doré C, Musso G, Julian LM, Kristof AS, Tam RY, Berman JN, Shoichet MS, Stanford WL. Tissue-Engineered Disease Modeling of Lymphangioleiomyomatosis Exposes a Therapeutic Vulnerability to HDAC Inhibition. Advanced Science (2023). 10(26): e2302611 Pubmed

 

Venkateshappa R, Hunter DV, Muralidharan P, Nagalingham RS, Huen G, Faizi S, Luthra S, Lin E, Cheng YM, Hughes J, Khelifi R, Dhunna DP, Johal R, Sergeev V, Shafaattalab S, Julian LM, Poburko D, Laksman Z, Tibbits GF, Claydon TW. Targeted activation of human ether-à-go-go-related gene channels rescues electrical instability induced by the R56Q+/- long QT syndrome variant. Cardiovascular Res. (2023). 119(15): 2522-2535 Pubmed

 

George E. Allen, Aaron S. Dhanda, and Lisa M. Julian. Emerging Methods in Modeling Brain Development and Disease with Human Pluripotent Stem Cells. Methods in Molecular Biology (2022). 2515:319-342. Pubmed

 

Erin Knock and Lisa M Julian. Building on a solid foundation: adding relevance and reproducibility to neurological modeling using human pluripotent stem cells. Front Cell Neurosci (2021). 15:767457. Pubmed

 

Julian LM and Stanford WL. Organelle cooperation in stem cell fate: lysosomes as emerging regulators of cell identity. Front Cell Dev Bio. (2020). 8:591. Pubmed

 

Sean P. Delaney, Lisa M. Julian, Adam Pietrobon, Julien Yockell-Lelièvre, Carole Dore, Ting T Wang, Valerie C Doyon, Angela Raymond, David A. Patten, Mary-Ellen Harper, Hongyu Sun, and William L. Stanford. Human pluripotent stem cell modeling of tuberous sclerosis complex reveals lineage-specific therapeutic vulnerabilities. (2020).

bioRxiv; doi: https://doi.org/10.1101/683359

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Huang T, Gonzalez YR, Qu D, Huang E, Safarpour F, Wang E, Joselin A, Im DS, Callaghan SM, Boonying W, Julian L, Dunwoodie SL, Slack RS, and Park DS. The pro-death role of Cited2 in Stroke is regulated by E2F1/4 transcription factors. J Biol Chem. (2019). 294(21): 8617-8629. Pubmed

 

Tam RY, Yockell-Lelièvre J, Smith LJ, Julian LM, Baker AEG, Choey C, Hasim MS, Dimitroulakos J, Stanford WL, and Shoichet MS. Rationally-Designed 3D Hydrogels Model Invasive Lung Diseases Enabling High Content Drug Screening. Advanced Materials (2018). Dec 27:e1806214. Pubmed

 

Chen Z, Pietrobon A, Julian LM, and Stanford WL. Somatic cell epigenetic reprogramming: molecular mechanisms and therapeutic potential. In D. Palacios (Ed), Epigenetics and Reprogramming (2018). Elsevier. Link

 

Lavictoire SJ, Gont A, Julian LM, Stanford WL, Vlasschaert C, Gray D, Jomaa D, Lorimer IAJ. Engineering PTEN-L for cell-mediated delivery. Molecular Therapy – Methods and Clinical Development (2017). 9:12-22. Pubmed

 

Lisa M Julian, and William L. Stanford. Reprogramming patient-derived tumour cells 

generates model cell lines for tuberous sclerosis-associated lymphangioleiomyomatosis. Oncoscience (2017). 4(11-12):170-172. Pubmed

 

Julian LM, Delaney SP, Wang Y, Goldberg AA, Doré C, Yockell-Lelièvre J, Tam RY, Giannikou K, McMurray F, Shoichet MS, Harper ME, Henske EP, Kwiatkowski DJ, Darling TN, Moss J, Kristof AS, Stanford WL. Human Pluripotent Stem Cell-Derived TSC2-Haploinsufficient Smooth Muscle Cells Recapitulate Features of Lymphangioleiomyomatosis. Cancer Research (2017). 77(20):5491-5502. Pubmed

 

Julian LM, McDonald AC, and Stanford WL. Direct reprogramming with SOX factors: masters of cell fate. Current Opinion in Genetics & Development (2017). 46:24-36. Pubmed

 

Julian LM, Carpenedo RL, Rothberg JL, and Stanford WL. Formula G1: Cell cycle in the driver’s seat of stem cell fate determination. Bioessays (2016). 38(4):325-332. *Journal cover. Pubmed

 

Carpenedo RL, Julian LM, and Stanford WL. Human pluripotent stem cells. Methods (2016). 101:1-3. Pubmed

 

Lisa M Julian and Alexandre Blais. Transcriptional control of stem cell fate by E2Fs and pocket proteins. Front Genetics (2015). 6:161. Pubmed

 

Lisa M Julian, Yubing Liu, Catherine A Pakenham, Delphie Dugal-Tessier, Vladimir Ruzhynsky, Sooin Bae, Shih-Yin Tsai, Gustavo Leone, Ruth S Slack, and Alexandre Blais. Tissue-specific Targeting of Cell Fate Regulatory Genes by E2f Factors. Cell Death & Differentiation (2016). 23(4):565-575. Pubmed

 

Sean P Delaney, Lisa M Julian, and William L Stanford. The neural crest lineage as a driver of disease heterogeneity in Tuberous Sclerosis Complex and Lymphangioleiomyomatosis. Front Cell Dev Biol (2014). 2:69. Pubmed

 

Julian LM, Vandenbosch R, Pakenham CA, Andrusiak MG, Nguyen AP, McClellan KA, Svoboda DS, Lagace DC, Park DS, Leone G, Blais A, and Slack RS. Opposing regulation of Sox2 by cell cycle effectors E2f3a and E2f3b in neural stem cells. Cell Stem Cell (2013). 12(4):440-452. Pubmed

 

Ghanem N, Andrusiak MG, Svoboda DS, Allafi SM, Julian LM, McClellan KA, De Reptigny Y, Kothary R, Ekker M, Blais A, Park DS, and Slack RS. The Rb/E2F pathway modulates neurogenesis through direct regulation of the Dlxi/Dlx2 bigene cluster. J Neuroscience (2012). 32(24):8219-8230. Pubmed

 

Andrusiak MG, McClellan KA, Dugal-Tessier D, Julian LM, Rodrigues SP, Park DS, and Slack RS. Rb/E2F regulates expression of neogenin during neuronal migration. Mol Cell Biol (2010). 31(2):238-247. Pubmed

 

McClellan KA, Vanderluit JL, Julian LM, Andrusiak MG, Dugal-Tessier D, Park DS, and Slack RS. The p107/E2F pathway regulates fibroblast growth factor receptor 2 responsiveness in neural precursor cells. Mol Cell Biol (2009). 29(17):4701-4713. Pubmed

 

Seifried LA, Talluri S, Cecchini M, Julian LM, Mymryk JS, and Dick FA. pRB-E2F1 complexes are resistant to adenovirus E1A-mediated disruption. J Virology (2008). 82(9):4511-4520. Pubmed

 

LM Julian, O Palander, LA Seifried, JEG Foster, and FA Dick. Characterization of an E2F1-specific binding domain in pRB and its implications for apoptotic regulation. Oncogene (2008). 27(11):1572-1579. Pubmed

 

Isaac CE, Francis SM, Martens AL, Julian LM, Seifried LA, Erdmann N, Binne UK, Harrington L, Sicinski P, Berube NG, Dyson NJ, and Dick FA. The retinoblastoma protein regulates pericentric heterochromatin. Mol Cell Biol (2006). 26(9):3659-3671. Pubmed